Infection, Part I is the fourth episode of the eighth season and the 163rd overall episode of Chicago Fire. It is the first part of a three-part crossover event with Chicago Med and Chicago P.D. The event starts with Infection, Part I, continues with Infection, Part II, and concludes with Infection, Part III.
Summary[]
A rare-but-deadly bacteria takes its toll on numerous victims around the city, leaving Chicago’s finest first responders to work together alongside the CDC to resolve the dangerous situation. Following a fire at a local university that ties into the outbreak, Severide has suspicions that something bigger is happening.
Cast[]
Main Cast[]
- Jesse Spencer as Captain Matthew Casey
- Taylor Kinney as Lieutenant Kelly Severide
- Kara Killmer as Paramedic Sylvie Brett
- David Eigenberg as Lieutenant Christopher Herrmann
- Joe Minoso as Firefighter Joe Cruz
- Christian Stolte as Firefighter Randy "Mouch" McHolland
- Miranda Rae Mayo as Firefighter Stella Kidd
- Annie Ilonzeh as Paramedic Emily Foster
- Daniel Kyri as Firefighter Darren Ritter
- Alberto Rosende as Firefighter Blake Gallo
- Eamonn Walker as Battalion Chief Wallace Boden
Crossover Cast[]
- Jason Beghe as Sergeant Hank Voight
- Jesse Lee Soffer as Detective Jay Halstead
- Tracy Spiridakos as Detective Hailey Upton
- Marina Squerciati as Detective Kim Burgess
- Patrick John Flueger as Detective Adam Ruzek
- LaRoyce Hawkins as Detective Kevin Atwater
- Lisseth Chavez as Officer Vanessa Rojas
- Aaron Serotsky as Dr. David Seldon
- Nick Gehlfuss as Dr. Will Halstead
- Yaya DaCosta as Nurse April Sexton
- Torrey DeVitto as Dr. Natalie Manning
- Marlyne Barrett as Nurse Maggie Lockwood
- Dominic Rains as Dr. Crockett Marcel
- S. Epatha Merkerson as Executive Director Sharon Goodwin
Recurring Cast[]
- Randy Flagler as Firefighter Harold Capp
- Anthony Ferraris as Firefighter Tony Ferraris
- Tim Hopper as Captain Tom Van Meter
- Steve "Chik" Chikerotis as Deputy District Chief Steve Walker
- Michele Martinez as Paramedic Michele Martinez
- Kristen Gutoskie as Chloe Allen
- Michelle Bester as Paramedic Brady
Guest Cast[]
- Julian Hester as John Sorenstein
- Andrew White as Bruno Geller
- Eunji Kim as Veronica Song
- Dylan Obrochta as Stuart Anderson
- Eileen Galindo as Mama Alma Garcia
- Ann Hagemann as Lila
- Bryan Eng as Harrison
- Ahmed Lucan as Jared
- Bryan Bosque as Paramedic
- Robin Robinson as Newscaster
- Colt Cabana as Hazmat Leader
- Marguerite Genard as Hazmat Member
- Lucy Carapetyan as Administrator
- Calvin Thomas as Tailgater
- Joe McCauley as Mailman
- Gillian Hemme as College Student
- Julia Germeroth as Clerk
- Tiera Dudley as Woman